If you’re currently on medication and thinking about trying CBD, then here’s what you need to know about how CBD interacts with other medicines. It seems that everywhere you look, people are talking about cannabidiol (CBD) and its natural properties. While research into CBD is still ongoing, some promising research studies have got people around the world excited about CBD’s natural features.
While CBD is a natural product that many people are considering taking, you also need to think about the other medications that you might be taking. It’s not uncommon for people to be taking multiple drugs at the same time, and how they interact together is very important for your health.
If you take the wrong combinations of medications, it can lead to serious health complications, so you must understand how different compounds interact together. If you are taking multiple drugs and thinking of trying CBD, you should always speak to your doctor or healthcare professional first.
Research has shown us that CBD has an excellent safety profile!
While we are still uncovering different uses for CBD, studies have shown us that even in larger doses, cannabidiol is well tolerated by the body. In one study, doses of up to 160mg per day were tolerated with minimal side-effects.
To help you understand, the average dose of CBD oil that people take is approximately 24mg of CBD per day.
The World Health Organization (WHO) has also weighed into the debate on CBD, releasing their results from investigations into the safety profile of CBD. The WHO review into CBD looked at a large variety of different reports and studies into CBD as well as both clinical and preclinical trials.
‘CBD is generally well tolerated with a good safety profile. Reported adverse effects may be as a result of drug-drug interactions between CBD and patients’ existing medications. Several countries have modified their national controls to accommodate CBD as a medicinal product. To date, there is no evidence of recreational use of CBD or any public health-related problems associated with the use of pure CBD.’
How does CBD interact with other medications?
Like most medications, CBD has to be metabolized in the liver before it is processed and distributed throughout the body. When you take CBD oils and other CBD edibles, they pass through the digestive system first and then onto the liver. Not all of the CBD makes it through the digestive system, and as much as 50% can be lost in the digestive system.
The next step in the process is for the CBD to be processed by the liver. The liver utilizes special enzymes that break the cannabidiol down into smaller pieces and send them around the body through the circulatory system.
Problems only start to occur when you take CBD alongside other medications because CBD takes all of the liver’s attention. The cytochrome P450 enzymes in the liver focus all of their attention on the CBD and ignore any other medication that’s waiting to be broken down.
It’s this delay in processing that adverse effects can begin to be an issue. Whenever dosages of medications or strengths of medications are taken into consideration, how long the medication takes to be broken down is also carefully considered. If drugs stay in the liver too long, then potential side-effects can be exasperated.
The potential side-effects and interactions between CBD and other medications are still ongoing
Any medication that you take that is metabolized by the cytochrome P450 enzymes in the liver could be adversely affected by taking CBD at the same time. Antidepressants, beta-blockers, antibiotics, steroids, and antihistamines are all medicines that are metabolized by the P450 enzyme.
If you’re taking any of these medications, you should seek medical advice before starting to take any CBD products. It’s also a good idea to start slowly with any CBD products and gradually increase your dosage and the frequency of the dosage over several weeks. This will help ensure that you are suited to CBD and reduce the chances of any harmful side-effects.
It’s important to note, however, that just because those medications could interact with CBD, it doesn’t mean that they will. That’s why it’s essential to speak with your doctor before you start taking CBD if you’re currently taking any medication. Your doctor will have a much better idea of any potential adverse interactions that could occur.